PhD opportunity: COSMIC, COmbatting disorders of adaptive immunity with Systems MedICine

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PhD opportunity: COSMIC, COmbatting disorders of adaptive immunity with Systems MedICine


IBM - Zurich Research Lab



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Job description

A PhD research position is available at IBM – Zurich Research Laboratory, as a part of the H2020 COSMIC consortium, focused on understanding disorders of the adaptive immune system.

Background: EU countries face large health challenges to combat chronic diseases. Recently, systems medicine has emerged as a promising discipline to accelerate the translation of basic research into applications for improved diagnostics and personalized treatment. Its power arises from the integration of laboratory and computational approaches crossing research disciplines and sectors to solve clinical questions.

Approach: COSMIC will focus on B-cell neoplasia and rheumatoid arthritis, prototypical diseases originating from abnormal functioning of immune cells, often resulting in similar antigen specificities. The successful candidate will develop new algorithms to understand the molecular mechanisms of these diseases, and to identify strategies for optimal personalized patient treatment.

Keywords: Mechanistic models of cancer, Machine learning, Deep learning, Statistical inference.

Profile requirements

  • Strong background in computer science, mathematics, physics or similar.
  • Working knowledge of C or C++.
  • Working knowledge of Matlab, R or equivalent.
  • Comfortable knowledge of statistics and mathematical modeling.

In addition, the following experience would be helpful, but not essential:

  • Experience in machine learning, deep learning, big data analysis, and high performance computing.
  • Experience in systems biology or systems medicine.

Position contact information

Name: Maria Rodriguez Martinez

IBM Research - Zurich Saumerstrasse 4
Rueschlikon, Zurich 8803

Phone: +41447248111