A recent initiative of NEXUS is the establishment of an organoid biobank. Organoids are stem cell-derived epithelial “mini organs” from human normal and diseased tissues and mouse disease models. They can be indefinitely propagated, and used for the profiling of biomolecules, functional studies and investigations of therapy responses. With this initiative, researchers will have access to an advanced cell system to tackle challenging projects to understand and treat human disease.
Together with Swiss hospitals, NEXUS is involved in the development of decision support systems for oncologists, which are based on the analysis of whole exome and whole genome sequencing data from paired patient tumour/normal samples.
Below are two flagship projects of the Competence Center Personalized Medicine (CC-PM) that are performed in collaboration with NEXUS: