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Anna-Sapfo Malaspinas
Evolutionary Genomics
University of Bern
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What do we do?

Ancient and modern DNA research have both entered the genomics era. At the Evolutionary Genomics Group (EGG)/Computational Paleogenomics Group (CPG), we aim at characterizing evolutionary processes (genetic drift, natural selection, migration and mutation) while relying on genomics data from both modern and ancient samples. We develop analytical and computational methods to analyze and interpret time sampled data and we apply those methods to novel ancient DNA datasets via collaborative projects. Our work should allow to quantify and time adaptive and migration events –notably related to the human colonization of the world - while generating unique datasets.

Main publications 2016

  • AS Malaspinas, MC Westaway, C Muller, VC Sousa, O Lao, I Alves, et al. A genomic history of Aboriginal Australia. Nature 538, 207–214
  • AS Malaspinas. Methods to characterize selective sweeps using time serial samples: an ancient DNA perspective. Molecular ecology 25 (1), 24-41

Our research topics: