Statistical Genomics and Epigenomics
We are members of EpiGeneSys and collaborate with experimental groups using in vitro and in vivo differentiation systems to study the genetic and epigenetic regulation of gene expression and cell fate decisions.
MetastasiX – Systems Biology of Breast Cancer
More information about our research
We study regulation of gene expression using high-throughput sequencing data. The heatmap here shows a re-analysis of RNA-seq data from Menet et al., 2012, showing RNA levels of oscillating genes in mouse liver.
Exon-Intron split analysis (EISA) compares changes of exonic and intronic read counts in RNA-seq data and characterizes transcriptional and post-transcriptional gene regulation.