Video – Building the national research infrastructure

SIB was mandated to play a pivotal role in the Swiss Personalized Health Network (SPHN), a national initiative launched in January 2017.
Torsten Schwede, Head of SIB’s Personalized Health Informatics group, presents some of the challenges and the expertise needed to bring Switzerland at the forefront of personalized health.

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Virus bioinformatics on the rise: SIB is among the founders of a dedicated European Centre

Most of today's bioinformatics is focused on bacteria and eukaryotic model organisms, while there is an urgent need for applying and developing computational approaches in the field of virology. With the founding of the European Virus Bioinformatics Centre (EVBC) in Jena, on 8 March 2017, by researchers from 10 European countries, the very best of European research from virology and bioinformatics has been brought together.

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Oncobench: one day gained to fight cancer

When it comes to fighting cancer, obtaining a diagnosis a day earlier, as well as saving one full day per week of clinical lab professionals’ precious time, can have important benefits for patients, hospitals and health insurance alike. This and other advances have been made possible by a tool developed by SIB and the Clinical Pathology Service of the Geneva University Hospitals (HUG), according to a recent satisfaction survey.

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The Drug Design Workshop: tomorrow’s drugs at your fingertips

Bringing medicinal chemistry and bioinformatics to the layman, by using a didactic online platform based on professional tools, is the goal of the Drug Design Workshop. Developed in 2015 by SIB researchers, together with training and outreach officers, the workshop is both in English and French and has already successfully taken over 1,500 people, of all ages and background, on a journey to design/create the drugs of tomorrow.

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Video – RHAPSODY, a project to fight diabetes

Last September, we were announcing SIB’s participation in a European public-private partnership on Risk Assessment and Progression of Diabetes (RHAPSODY).
Watch this short video to learn more about SIB’s role in the project.

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SIB is part of a global coalition to sustain core data resources

The advancement of science, medicine and the society as a whole depends on crucial data resources, such as DNA sequence repositories or protein knowledgebases.
However the clock is ticking for most of these resources, as only a fraction benefit from long-term financial stability. Among the identified threats figure short-term funding, grant competition and shifting political priorities.

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Emmanouil Dermitzakis receives prestigious award

SIB’s Group Leader Emmanouil Dermitzakis, Professor of Genetics in the Department of Genetic Medicine and Development (University of Geneva Medical School), was awarded the 2017 Bodossaki Foundation Scientific Award in the field of Biosciences (Medicine or Biology).

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DNA, a (hyper)winding road

When it comes to packaging large amounts of information into tiny volumes, biology and physics often buddy up to reach creative solutions. The problem is even more complex with DNA, as the compacted information must also remain accessible to the proteins in charge of transcription.

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Latest Protein Spotlight: Something else

Knives were crafted to cut. Yet how many of us use them to slit an envelope. Or prise open a lid. Nature too has its ways of perverting a design so that its initial role is altered to become another. This is exactly what happened to a protein known as osteocrin.

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Latest Protein Spotlight: A walk on the rough side

Life can be hard. There are times when you find yourself in the most unfriendly circumstances and, more often than not, the best way to deal with the situation is to find your own solution and wriggle your own way out. Living species are the most imaginative of beings when it comes to designing defence mechanisms.

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Focus on Clinical Bioinformatics: Bridging the gap between data science and medicine

“Stick out your tongue and say... ‘omics’”.
In addition to patients’ vital signs or eating habits, molecular profiling data is increasingly becoming part of the medical practitioners’ toolbox. But these ‘omics’ data pose novel challenges, for clinicians and scientists alike.

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SIB International Young Bioinformatician Award

Are you an early-career and outstanding bioinformatician? SIB is recognizing excellence through the SIB International Young Bioinformatician award - now open for international candidates! Check the conditions and apply online before 15 March. More

SIB accelerates the fight against diabetes with several pan- European projects

Recent advances in the fight against type 2 diabetes (T2D) result from a pan-European collaborative project, called IMIDIA, in which the SIB Swiss Institute of Bioinformatics is closely involved since 2010.

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Why am I shorter than you?

The answer to that question lies to some extent in our diet and environment, but mostly in our DNA (80%). Combining genome-wide association methods and an unmatched dataset of more than 700,000 participants, a recent study narrowed down the set of candidate changes to 83 variants, some of which altering the size by more than 2 cm.

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Marie Dangles
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Sylvie Clottu
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SIB Communications
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