RHAPSODY, a European symphony for personalized health of diabetes

Lausanne, 6 September 2016
The pan-European project RHAPSODY reunites researchers and experts from 26 partner Institutions, in both the public and private sectors, to improve the diagnosis of and fight against type 2 diabetes (T2D). SIB Swiss Institute of Bioinformatics is in charge of coordinating the integration of existing clinical data.

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Hairs, feathers and scales have a lot in common !

The potential evolutionary link between hairs in mammals, feathers in birds and scales in reptiles has been debated for decades. Today, researchers of the University of Geneva (UNIGE) and the SIB Swiss Institute of Bioinformatics, Switzerland, demonstrate that all these skin appendages are homologous: they share a common ancestry.

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We are not alone. From the day we are born, we carry with us hordes of microorganisms which, if all is going well, live off us while giving something in return. This micro-universe which is an integral part of our physiology has been called the microbiome.

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Winner of the SIB Best Lightning Talk Award

Congratulations to Lorenzo Gatti, from the Applied Computational Genomics Team in Zurich, who won the SIB Best Lightning Talk Award in recognition of his outstanding presentation entitled «As a stone thrown in a still pond: Describing human influenza dynamics and global circulation patterns after 2009 A/pH1N1 pandemic explosion»

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Genomics solutions to the riddle of the tobacco hornworm sphinx moth

Geneva, 12 August 2016 - Manduca sexta caterpillars
"Whooo ... are ... you?" asked the hookah-smoking caterpillar of Alice, in Wonderland. Asking the question of the caterpillar instead, an international team of scientists have published their findings from the sequencing, annotation, and exploration of the genome of the tobacco hornworm moth.

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Winners of the SIB Best Poster Award

Congratulations to the Proteome Informatics Group (represented by Julien Mariethoz - left) and the SIB Technology Group (represented by Vassilios Ioannidis - right) who won the Best Poster Award ex aequo at our SIB Days last week!

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Latest Protein Spotlight: Of plastic and men

Nature has extraordinary resources. Here we are trashing her land, sea and atmosphere - and have been for over a century now - with all sorts of chemistry she didn't ask for and which, sooner or later, will prove to be harmful to those who are putting it there.

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SIB’s virtual computational biology seminars now available online and open to everyone

The Computational Biology seminars organized by SIB on the campus of the University of Lausanne are now available online and open to everyone. These seminars represent a great opportunity for life scientists and clinicians to learn more about SIB’s research, expertise and resources.

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A non-invasive prenatal test for detecting rare chromosomal anomalies

Lausanne, 14 July 2016 - NIPT Technology
The Vital-IT group of the SIB Swiss Institute of Bioinformatics and led by Prof. Ioannis Xenarios has been involved in fine-tuning an existing non-invasive prenatal test (NIPT) with the hope of detecting a broader array of chromosomal anomalies.

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Latest Protein Spotlight: The shape of harm

Sometimes we are forced to see things differently. But it is never easy because we are creatures of habit and, like it or not, shackled by what we were first led to believe.

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The Science & Music project Opus 23 steps forward with a CD recording

Can music help us understand science? SIB asked the French composer Olivier Calmel to express the human genome complexity through a string quartet. The work was performed during several Science & Music events and was recorded by the Ramsès Quartet. The CD is now available!

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The latest SIB Profile 2016 / Annual Report 2015 is out

SIB’s scope of activities continues to grow in all fields of bioinformatics – from proteomics and genomics, to metabolomics and the crucial domain of personalized health. Find out all our 2015 highlights in our latest annual report.

Latest Protein Spotlight: On releasing tension

Like life, cells are subject to continuous change. Nothing in the vicinity of a cell remains still - unless death has interrupted its course. And the same goes for the inside of each cell. All sorts of molecules are being shuttled from one part to another, after having been created or on their way to being degraded.

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Christophe Dessimoz – Orthology: you can’t improve what you can’t measure

Standardized benchmarking in the quest for orthologs, Nature Methods, advanced online publication April 2016, doi:10.1038/nmeth.3830

A lot of effort is put into designing methods to find genes – known as orthologs – that are directly related in different species. Unearthing orthologs is essential for many comparative, evolutionary and functional genomic analyses, and the higher the accuracy the better the analyses.

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