Latest Protein Spotlight issue: Discerning change

Outside, clouds glide across the horizon. A man on the street below seems in a hurry. Two cars and a lorry drive past him. And a sparrow lands on the windowsill. As you get up to see it closer, a pencil rolls off the end of the table and falls to the floor. None of this may seem particularly eventful to you but it does take a very intricate network of cells to process the surrounding information so that you can see it all happening.

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SIB joins the fight against Zika

A page dedicated to the Zika virus has recently been published by ViralZone – one of SIB’s core knowledge resources on virus diversity. The Zika virus is an emerging pathogene. As such, most knowledge referring directly to it is scarce, or must be retrieved from viruses of the same family in various articles, books, databases etc.

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A history of Swiss-Prot


In the late 70s, DNA and protein sequences started being produced quite easily and with them came the need for storage and analysis tools.

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Genome of the bed bug explains insecticide resistance and brutal sex

Sequencing the bed bug genome has shed light on how to devise strategies against their resistance to insecticides - this is the result of the work of two different groups of scientists - including members of the SIB Swiss Institute of Bioinformatics. The groups recently decoded the bed bug’s genome in the search for new approaches to combat the spread of bed bugs. Both articles were published early February in Nature Communications.

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Swiss-Prot celebrates its 30 years

On the occasion of the Biocuration Conference 2016 in Geneva, the Swiss-Prot protein database will be celebrating its 30th Anniversary. Geneva is the town of origin of the SIB Swiss Institute of Bioinformatics and the cradle of the most important protein encyclopedia in the world.

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Latest Protein Spotlight issue: Shaping Life

We take our shape for granted. As we do the contours of our eyes and the curves of our heart. But for everything to be sculpted the way Nature has found it best for us to be, cells need to know when to multiply and when to stop multiplying, in addition to knowing how to remain close to one another while dealing with external forces such as the gravitational pull.

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SIB Group leaders receive Best Paper Award at Bioinformatics Conference in San Francisco

Philipp Bucher and Bernard Moret – both Group leaders at the SIB Swiss Institute of Bioinformatics and at the EPFL – as well as members of their team received the Best Paper Award for "A Maximum-likelihood approach for building cell-type trees by lifting" at the fourteenth Asia Pacific Bioinformatics Conference in San Francisco.

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Harmful mutations have accumulated during early human migrations out of Africa

Lausanne, 11 January 2016 - The further a population moves away from its place of origin, the more harmful mutations it will carry. This is the result of a study conducted by Laurent Excoffier, Group leader at the SIB Swiss Institute of Bioinformatics and Professor at the University of Bern, and his team, as part of an international collaboration led by Brenna Henn from Stony Brook University and Carlos Bustamante from Stanford University.

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Tick tock - sequencing the tick genome could help defuse the Lyme disease time bomb

Geneva, 10 February 2016 - After a decade-long research effort the genome of the deer tick has been sequenced by an international team of scientists, including researchers from the SIB Swiss Institute of Bioinformatics. Studying the tick genome sheds light on how ticks function and will help to develop novel tick control programmes by interfering with the processes of disease transmission.

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