A deeper look on brain ageing: Further Study on Late-Onset Alzheimer Disease, the most common type of dementia

The SIB Swiss Institute of Bioinformatics will be one of the actors of a recently launched Aging Systems Biology project (AgedBrainSysBio), a European collaborative research project funded by the European Commission under the Health Work Programme of the 7th Framework Programme. The consortium which gathers 14 academic and industrial partners from different countries will combine their efforts to study human brain ageing and Alzheimer’s disease, the most common type of dementia, a chronic and neurodegenerative disease, for which no cure exists.

AgedBrainSysBio will have the challenge to combine existing large-scale data, results and technologies with databases on ageing. Using integrative systems biology, comparative genomics and proteomics, researchers will study interactions and pathways involved in normal and disease conditions. The ultimate goal being to identify and validate new druggable targets for aging cognitive defects cure.

The Aging Systems Biology project will benefit from the SIB Swiss Institute of Bioinformatics, who will provide its renowned expertise in biocuration, computational system modeling and data integration approaches.